JOHN F. DRAPIEWSKI, M.D., F.A.C.P.; SANFORD B. STERNLIEB, M.D.; ROBERT JONES, M.D.
The first case of primary amyloidosis was reported by Wilks1 in 1856. Ninety-six years later Higgins and Higgins2 had gathered a total of 71 cases. Like any disease the clinical diagnosis of which depends upon a sensitive index of suspicion, primary amyloidosis is perhaps less rare than these figures indicate. Yet it is certainly not a common disease, and primary amyloidosis complicated by spontaneous rupture of the spleen is most unusual. The first such case was reported by Wiley, Teeter and Schnabel.3 Recently Frohner,4 in a discussion of trauma and preëxisting disease with rupture of the spleen, did not include
DRAPIEWSKI JF, STERNLIEB SB, JONES R. PRIMARY AMYLOIDOSIS WITH SPONTANEOUS RUPTURE OF THE SPLEEN AND SUDDEN DEATH1. Ann Intern Med. ;43:406–412. doi: 10.7326/0003-4819-43-2-406
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Published: Ann Intern Med. 1955;43(2):406-412.
Adrenal Disorders, Endocrine and Metabolism, Hospital Medicine.
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