C. J. DELOR, M.D., F.A.C.P.; R. W. MARTZ, M.D.
Destructive bone changes have not been reported previously in Weber-Christian disease. However, Steinberg1 has recently reported two cases with changes in the bone marrow.
Pfeifer2 in 1892 was the first to describe a patient with subcutaneous nodules in the extremities and trunk which were movable, red, painful, and associated with fever. A similar condition was reported by Gilchrist and Ketron3 in an eight year old girl in 1916. In their patient the lesions were confined to the lower extremities and were associated with febrile episodes and loss of appetite. The contour of the legs was strikingly distorted, and
DELOR CJ, MARTZ RW. WEBER-CHRISTIAN DISEASE WITH BONE INVOLVEMENT1. Ann Intern Med. ;43:591–598. doi: 10.7326/0003-4819-43-3-591
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Published: Ann Intern Med. 1955;43(3):591-598.
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