C. LOCKARD CONLEY, M.D.; JULIUS R. KREVANS, M.D.
Criteria for the diagnosis of pernicious anemia must be reëvaluated in light of the changing pattern of this disease. The profound physical abnormalities and extreme hematologic aberrations associated with classic severe pernicious anemia are not often encountered in modern practice. There are two reasons for this alteration in the character of the disorder. In the first place, patients tend to consult their physicians early, at a time when symptoms may seem inconsequential. The only complaint may be slight weakness or fatigue, or perhaps soreness of the tongue. There may be no detectable pallor at this time, and even if the
CONLEY CL, KREVANS JR. NEW DEVELOPMENTS IN THE DIAGNOSIS AND TREATMENT OF PERNICIOUS ANEMIA12. Ann Intern Med. ;43:758–766. doi: 10.7326/0003-4819-43-4-758
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Published: Ann Intern Med. 1955;43(4):758-766.
Hematology/Oncology, Red Cell Disorders.
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