E. RICHARD HARRELL, M.D.; FLORANTE C. BOCOBO, M.D.; ARTHUR C. CURTIS, M.D., F.A.C.P.
Stilbamidine and 2-hydroxystilbamidine are now widely accepted as the treatment of choice for the systemic fungus disease, North American blastomycosis. Schwarz and Goldman1 recently reported from an epidemiologic study of blastomycosis in the United States that there were 39 cases of this disease treated with the stilbamidines during the first six months of 1953. There is a steady increase in the number of cases of blastomycosis treated with stilbamidine reported in the medical literature. These aromatic diamidines have also been used successfully in the treatment of actinomycosis2 and sporotrichosis,3 and have been tried (with poor results) in coccidioidomycosis,4, 5 cryptococcosis6
HARRELL ER, BOCOBO FC, CURTIS AC. A STUDY OF NORTH AMERICAN BLASTOMYCOSIS AND ITS TREATMENT WITH STILBAMIDINE AND 2-HYDROXYSTILBAMIDINE*. Ann Intern Med. 1955;43:1076–1091. doi: https://doi.org/10.7326/0003-4819-43-5-1076
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Published: Ann Intern Med. 1955;43(5):1076-1091.
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