GEORGE H. WAHLE JR.; DONALD G. MCKAY
In a recent analysis of the causes of death in patients with epidemic hemorrhagic fever Giles et al.1 found that acute renal failure, shock, dehydration, pulmonary edema and infection, hemorrhage into the gastrointestinal tract and central nervous system, and electrolyte disturbances were among the basic and contributory lethal factors in this disease. Panhypopituitarism can now be added to this list as a late sequela. This eventuality was certainly to be expected in view of the pathologic observations of Hullinghorst and Steer2 and Lukes3 in the more acute phases of the disease. These authors found that 72 to 77% of the
WAHLE GH, MCKAY DG. PANHYPOPITUITARISM FOLLOWING EPIDEMIC HEMORRHAGIC FEVER. II. PATHOLOGIC ANATOMY*. Ann Intern Med. 1955;43:1320–1330. doi: https://doi.org/10.7326/0003-4819-43-6-1320
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© 2019
Published: Ann Intern Med. 1955;43(6):1320-1330.
DOI: 10.7326/0003-4819-43-6-1320
Infectious Disease, Neurology.
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