H. SCHAFER, M.D.; J. M. BLAIN, M.D.; R. CEBALLOS, M.D.; R. J. BING, M.D., F.A.C.P.
Essential pulmonary hypertension is a condition in which the elevation in pulmonary artery pressure results from an increase in the vascular resistance in the lung. The exact cause of the pulmonary vascular changes is not definitely established, but the possibility exists that in some instances repeated asymptomatic pulmonary embolizations can produce the vascular changes found in this disease.3, 44 Other terms for this condition are pulmonary vascular obstruction syndrome or primary pulmonary hypertension.3, 12, 15, 16, 17, 38
Prior to the introduction of cardiac catheterization, primary pulmonary hypertension was considered rare. In 1931 McCallum reported one case in 12,000 autopsies
SCHAFER H, BLAIN JM, CEBALLOS R, et al. ESSENTIAL PULMONARY HYPERTENSION: A REPORT OF CLINICAL-PHYSIOLOGIC STUDIES IN THREE PATIENTS, WITH DEATH FOLLOWING CATHETERIZATION OF THE HEART*. Ann Intern Med. 1956;44:505–523. doi: https://doi.org/10.7326/0003-4819-44-3-505
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Published: Ann Intern Med. 1956;44(3):505-523.
Cardiology, Pulmonary Hypertension, Pulmonary/Critical Care.
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