HENRY C. JOHNSON JR., M.D.; JOHN P. DOENGES, M.D.
The clinical task of differentiating intrahepatic from extrahepatic jaundice is a problem frequently encountered by both physicians and surgeons. The divergent therapeutic implications in the management of these two forms of jaundice make their differentiation imperative. Careful attention to the clinical history and physical findings, utilization of the growing number of available chemical tests of liver cell function1-4 and selective use of needle biopsy of the liver5-7 have made it possible to arrive at the correct diagnosis in a high percentage of such cases. Of particular interest, however, and offering unusual diagnostic difficulty, are certain instances of acute or subacute
JOHNSON HC, DOENGES JP. INTRAHEPATIC OBSTRUCTIVE JAUNDICE (PRIMARY CHOLESTASIS), A CLINICOPATHOLOGIC SYNDROME OF VARIED ETIOLOGY: A REVIEW WITH OBSERVATIONS OF THE USE OF CORTICOTROPIN AS A DIAGNOSTIC TOOL1. Ann Intern Med. 1956;44:589–616. doi: 10.7326/0003-4819-44-4-589
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Published: Ann Intern Med. 1956;44(4):589-616.
Biliary Disorders, Gastroenterology/Hepatology.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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