ROBERT J. MATTHEWS, M.D.; FRED T. DARVILL JR., M.D.
Insufficiency of the aortic valve is caused most frequently by rheumatic fever or syphilis. Occasionally aortic insufficiency may be a result of bacterial endocarditis, dilatation of the aortic valve ring, hypertension and aortic arteriosclerosis, dissecting aortic aneurysm or trauma. No mention is made in the commonly used texts of cardiology, medicine and pathology of fenestrations of the aortic valve cusps as a cause of aortic insufficiency or of spontaneous aortic valve cusp rupture.1, 2, 3, 4, 5 In fact, the literature on fenestrations of the semilunar valves is quite scant. In 1897, a study of 4,252 autopsies on mentally
MATTHEWS RJ, DARVILL FT. FENESTRATIONS OF THE AORTIC VALVE CUSPS AS A CAUSE OF AORTIC INSUFFICIENCY AND SPONTANEOUS AORTIC VALVE CUSP RUPTURE*. Ann Intern Med. 1956;44:993–1002. doi: https://doi.org/10.7326/0003-4819-44-5-993
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Published: Ann Intern Med. 1956;44(5):993-1002.
Cardiology, Emergency Medicine, Valvular Heart Disease.
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