H. D. BRAINERD, M.D., F.A.C.P.; L. M. CECIL, M.D.
The importance of pyelonephritis as a cause of illness and death has only recently become fully appreciated. Not only are infections of the urinary tract second in frequency to those of the respiratory tract, but also they commonly lead to serious or fatal sequelae. Longcope and Winkenwerder1 first emphasized the rôle of chronic pyelonephritis in the production of malignant hypertension. Their observations were further expanded by those of Weiss and Parker,2 who also suggested the relationship of chronic or healed pyelonephritis to both benign and malignant hypertension. Pyelonephritis, active or healed, is found in 14 to 20% of autopsies.2-4 Furthermore,
BRAINERD HD, CECIL LM. OBSERVATIONS ON THE PATHOGENESIS, COURSE AND TREATMENT OF NONOBSTRUCTIVE PYELONEPHRITIS1. Ann Intern Med. 1956;45:232–241. doi: 10.7326/0003-4819-45-2-232
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Published: Ann Intern Med. 1956;45(2):232-241.
Infectious Disease, Nephrology, Urinary Tract Infection.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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