FELIX WRÓBLEWSKI, M.D., F.A.C.P.; GEORGE JERVIS, M.D.; JOHN S. LADUE, M.D., F.A.C.P.
Glutamic oxaloacetic transaminase (GO-T) is widely distributed in animal and human tissues. Its greatest activity has been found in homogenates of heart muscle, skeletal muscle, brain, liver and kidney, the relative activities varying in different species (table 1). This enzyme activity has been found in all animal and human sera tested, and the activities are comparable whether determined chromatographically,1 spectrophotometrically2 or colorimetrically3 (figure 1). It has been demonstrated that serum
glutamic oxaloacetic transaminase (SGO-T) activity increases two to 20 times following acute myocardial infarction,4 and may rise to 20 to 500 times normal in acute hepatitis due to toxic
WRÓBLEWSKI F, JERVIS G, LADUE JS. THE DIAGNOSTIC, PROGNOSTIC AND EPIDEMIOLOGIC SIGNIFICANCE OF SERUM GLUTAMIC OXALOACETIC TRANSAMINASE (SGO-T) ALTERATIONS IN ACUTE HEPATITIS*. Ann Intern Med. 1956;45:782–800. doi: https://doi.org/10.7326/0003-4819-45-5-782
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Published: Ann Intern Med. 1956;45(5):782-800.
Gastroenterology/Hepatology, Liver Disease.
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