PAUL WINCHELL, M.D.
A group of chronic pulmonary diseases showing diffuse thickening of the alveolar septa has been shown to result in impairment of alveolar-capillary diffusion.1 The usual example of the syndrome presents with dyspnea, cyanosis, polycythemia and signs of chronic cor pulmonale, yet the partial pressure of carbon dioxide in the arterial blood is normal or low despite serious oxygen desaturation. Various causes for the chronic pulmonary disease responsible for this situation have been noted, including scleroderma, berylliosis, sarcoidosis and silicosis, but most of the cases seem to be cryptogenic pulmonary fibrosis. Reports concerning the effectiveness of adrenocorticotropic hormone in this group
WINCHELL P. ALVEOLAR-CAPILLARY DIFFUSION DEFECT: A CASE REPORT1. Ann Intern Med. 1956;45:957–962. doi: 10.7326/0003-4819-45-5-957
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Published: Ann Intern Med. 1956;45(5):957-962.
Cardiology, Coronary Risk Factors, Hospital Medicine, Hypertension, Interstitial Lung Disease.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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