RICHARD A. MACDONALD, M.D.; STANLEY L. ROBBINS, M.D.
The purpose of this paper is to call attention to the relatively unappreciated fact that nonbacterial thrombotic endocarditis has a clinical as well as a pathologic significance. Previous workers have studied this type of endocarditis from the standpoint of its histologic features, so that up to the present time there have been no studies correlating clinical and autopsy findings. From a review at the Mallory Institute of Pathology there is evidence that in a certain number of cases emboli may arise from the valvular vegetations and cause premortem infarction of organs. These infarctions in some cases contribute to death, and
MACDONALD RA, ROBBINS SL. THE SIGNIFICANCE OF NONBACTERIAL THROMBOTIC ENDOCARDITIS: AN AUTOPSY AND CLINICAL STUDY OF 78 CASES1. Ann Intern Med. ;46:255–273. doi: 10.7326/0003-4819-46-2-255
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Published: Ann Intern Med. 1957;46(2):255-273.
Cardiology, Endocarditis, Infectious Disease.
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