D. W. JOHNSTON, M.D.
Diffuse osteosclerosis is of varied etiology. Its pathogenesis is poorly understood. The clinical and x-ray features have become stereotyped in most cases, but do not as a rule suggest the etiology.
The conditions in which osteosclerosis, with or without hyperostosis, is seen, are:
2. Postoperative hyperparathyroidism.
3. Neoplasia, especially carcinoma of the prostate.
4. Hypervitaminosis D and, more rarely, A.
6. Phosphorus poisoning.
The known causes of overgrowth of periosteal bone are:
2. Healed scurvy.
3. Healed rickets.
The primary disorders of unknown etiology which cause increased density of bone are:
JOHNSTON DW. GENERALIZED OSTEOSCLEROSIS ASSOCIATED WITH DIABETES INSIPIDUS AND NEUROLOGIC SYMPTOMS1. Ann Intern Med. ;46:619–628. doi: 10.7326/0003-4819-46-3-619
Download citation file:
Published: Ann Intern Med. 1957;46(3):619-628.
Results provided by:
Copyright © 2019 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use