ROBERT S. NELSON, M.D., F.A.C.P.
The effects of ACTH and cortisone administration on patients with acute viral hepatitis are now well substantiated.1, 2, 4, 5 Foremost among these are the more rapid return of the serum bilirubin to normal and a marked increase in appetite. In a controlled series where patients were graded as to severity before being admitted to the study, cortisone administration resulted in a return of bromsulphalein retention, histologic abnormalities and signs and symptoms of the disease to normal more rapidly than in controls. Our experiences with ACTH led us to believe that this hormone was less desirable than cortisone, perhaps because
NELSON RS. PRESENT INDICATIONS FOR CORTISONE THERAPY IN ACUTE VIRAL HEPATITIS1. Ann Intern Med. ;46:685–695. doi: 10.7326/0003-4819-46-4-685
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Published: Ann Intern Med. 1957;46(4):685-695.
Gastroenterology/Hepatology, Infectious Disease, Liver Disease, Viral Hepatitis.
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