JAMES E. CASSIDY
Of the many consequences that meningococcal infection can produce,1 the most fearful is collapse. The multiple changes producing collapse proceed swiftly and with little warning. Unlike the shock attending trauma, hemorrhage or even adrenalectomy, in collapse neither blood and plasma transfusions nor the administration of plasma expanders or electrolyte solutions is of avail in treatment.
There is general familiarity with the acute adrenocortical damage which occurs in this disease. This may be variable in its degree and reversibility.2 The ultimate is, of course, obliterating hemorrhage. Regardless of severity, the insult to the adrenal cortex occurs precisely when demands of severe
CASSIDY JE. THERAPY IN COLLAPSE DUE TO MENINGOCOCCUS INFECTION1. Ann Intern Med. 1957;46:1099–1104. doi: 10.7326/0003-4819-46-6-1099
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Published: Ann Intern Med. 1957;46(6):1099-1104.
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