FRANK A. SOLOMON JR., M.D.; WILLIAM J. FEENEY
Articles have frequently appeared in the medical literature concerning pseudomembranous enterocolitis appearing as a complication of antibiotic therapy and caused by the development of bacteria resistant to the antibiotic employed for the treatment of the primary infection. Micrococcus pyogenes (Staphylococcus aureus) is the most consistently cited organism showing this resistance, and the incidence of this complication appears to be associated with the increased use of antibiotic drugs.
A review of the literature indicates that this is not a new entity. Finney, quoted from Penner and Bernheim,1 in 1893 reported a postoperative bloody diarrhea with death and autopsy findings of diphtheritic
SOLOMON FA, FEENEY WJ. PSEUDOMEMBRANOUS TRACHEOBRONCHITIS, PANCREATITIS AND ENTEROCOLITIS: REPORT OF A CASE COMPLICATING ANTIBIOTIC THERAPY OF PNEUMONIA AND SEPTICEMIA1. Ann Intern Med. ;47:161–172. doi: 10.7326/0003-4819-47-1-161
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Published: Ann Intern Med. 1957;47(1):161-172.
Gastroenterology/Hepatology, Infectious Disease, Multi-Organ Failure and Sepsis, Pancreatic Disease, Pneumonia.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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