ALVIN F. COBURN, M.D.
Physicians concerned with problems in the prevention of rheumatic fever have for more than half a century been confronted with two facts in the epidemiology of this disease. Wherever investigated, it has been observed that (a) outbreaks of rheumatic fever occurred following epidemics of "sore throats" or scarlatina, and (b) onset of the rheumatic state was confined almost exclusively to low income families. The first of these facts has been the subject of widespread research for more than a quarter of a century; the second has not yet received the attention that it deserves. Today I wish to deal briefly
COBURN AF. SOME BASIC, UNSOLVED PROBLEMS IN THE PREVENTION OF RHEUMATIC FEVER1. Ann Intern Med. 1957;47:402–417. doi: 10.7326/0003-4819-47-3-402
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Published: Ann Intern Med. 1957;47(3):402-417.
Infectious Disease, Rheumatology, Streptococcal Infections.
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