J. A. RIDER, M.D.; H. C. MOELLER, M.D.; T. L. ALTHAUSEN, M.D., F.A.C.P.; G. E. SHELINE, M.D.
Free gastric hydrochloric acid is essential for the production of peptic ulcer. It is possible by x-radiation to decrease or even abolish production of this acid, leading to subsequent healing of the ulcer. These observations serve as the rationale for the clinical use of x-ray therapy in the management of peptic ulcer.
Since Regaud et al.1 first studied the effect of x-ray on gastric secretion, numerous reports have indicated not only that irradiation will decrease gastric secretion, but also that, in general, the greater the exposure, the greater the decrease. In 1917 Bruegel2 reported the use of external x-ray radiation
RIDER JA, MOELLER HC, ALTHAUSEN TL, et al. THE EFFECT OF X-RAY THERAPY ON GASTRIC ACIDITY AND ON 17-HYDROXYCORTICOID AND UROPEPSIN EXCRETION*. Ann Intern Med. 1957;47:651–665. doi: https://doi.org/10.7326/0003-4819-47-4-651
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Published: Ann Intern Med. 1957;47(4):651-665.
Gastroenterology/Hepatology, Peptic Disease, Peptic Ulcer.
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