WESLEY W. SPINK, M.D., F.A.C.P.
Although the host-parasite relationship in many infectious diseases has been intensively studied in man, it is surprising how little is known about the fundamental mechanisms that are responsible for the resultant human illness. In conjunction with studies on the host-parasite factors in brucellosis, my associates and I have sought an answer to the question, What basic features contribute to the illness of a patient with this disease?
The purpose of this report is to point out the significance of bacterial hypersensitivity in the genesis of the illness caused by brucella organisms. Such a thesis has been proposed by others, not
SPINK WW. THE SIGNIFICANCE OF BACTERIAL HYPERSENSITIVITY IN HUMAN BRUCELLOSIS: STUDIES ON INFECTION DUE TO STRAIN 19 BRUCELLA ABORTUS1. Ann Intern Med. ;47:861–874. doi: 10.7326/0003-4819-47-5-861
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Published: Ann Intern Med. 1957;47(5):861-874.
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