EDMUND B. FLINK, M.D., F.A.C.P.; ROBERT MCCOLLISTER, M.D.; ANANDA S. PRASAD, M.D.; JAMES C. MELBY, M.D.; RICHARD P. DOE, M.D.
We shall attempt to present evidence that magnesium deficiency is a clinical problem, that it presents distinctive clinical features, and that it is not uncommon. A brief review of some of the facts about magnesium will be made and then evidence from the clinical course of patients, balance studies and correlation of findings will be presented.
An adult human body weighing 70 kg. contains about 21.0 gm. of magnesium, according to Shohl,1 and about 29 gm., according to Widdowson, McCance and Spray2 and Duckworth and Warnock.3 This discrepancy can be accounted for chiefly by differences in the skeletal content. Calculations
FLINK EB, MCCOLLISTER R, PRASAD AS, MELBY JC, DOE RP. EVIDENCES FOR CLINICAL MAGNESIUM DEFICIENCY1. Ann Intern Med. ;47:956–968. doi: 10.7326/0003-4819-47-5-956
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Published: Ann Intern Med. 1957;47(5):956-968.
Endocrine and Metabolism, Fluid and Electrolyte Disorders, Nephrology.
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