MARTIN L. CHARLES, M.D.; LOUIS J. VORHAUS, M.D.
The frequent development of pernicious anemia in patients who survive long enough following total gastrectomy is by now a well documented phenomenon. Indeed, as cases were reported and reviewed through the years,1-12 it became apparent that these patients can develop all the features of pernicious anemia, that the anemia usually takes at least two years to develop (and considerably longer in some cases), and that the patients respond well to antipernicious anemia therapy.
We feel the present case is of unusual interest not only because of the uncommonly long survival (11½ years) following total gastrectomy for carcinoma of the stomach
CHARLES ML, VORHAUS LJ. DELAYED DEVELOPMENT OF PERNICIOUS ANEMIA FOLLOWING GASTRECTOMY; HIGH FAMILIAL INCIDENCE OF CANCER: AN ILLUSTRATIVE CASE1. Ann Intern Med. 1957;47:1266–1276. doi: 10.7326/0003-4819-47-6-1266
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Published: Ann Intern Med. 1957;47(6):1266-1276.
Hematology/Oncology, Red Cell Disorders.
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