EARL H. ANTES
Thrombotic thrombocytopenic purpura has become recognized as a clinical entity only in recent years. This uniformly fatal disease, which may affect either sex at any age, is characterized by the clinical triad of hemolytic anemia, thrombocytopenic purpura and varied central nervous system abnormalities. The pathologic picture primarily shows changes in the arterioles, with the formation of poorly understood hyaline thrombi.
It is the purpose of this paper to review the available literature on this subject and to add a case report. This disease was thoroughly reviewed by Barondess1 in 1952, but further reported cases have helped to increase our knowledge
ANTES EH. THROMBOTIC THROMBOCYTOPENIC PURPURA: A REVIEW OF THE LITERATURE WITH REPORT OF A CASE1. Ann Intern Med. ;48:512–536. doi: 10.7326/0003-4819-48-3-512
Download citation file:
Published: Ann Intern Med. 1958;48(3):512-536.
Coagulopathies, Hematology/Oncology, Platelet Disorders.
Copyright © 2019 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use