HENRY G. KUPFER, M.D.; BRUCE J. EBBELS, M.D.; JOHN N. MILLER, M.D.; GEORGE W. THOMA, M.D.; SIMON RUSSI, M.D.
Considerable emphasis has been placed recently in the medical literature upon blood platelets and their functions. Much of the work centers around the multiple ways by which platelets influence the blood clotting mechanism. The prevailing evidence is that the first phase of coagulation is the one in which the platelets play their major role,1 although the additional functions of promoting capillary constriction and clot retraction must be included. A great deal more progress has been achieved in the study of thrombocytopenia than in its counterpart, thrombocythemia. This is undoubtedly due to the fact that a relatively small number of cases
KUPFER HG, EBBELS BJ, MILLER JN, et al. ESSENTIAL THROMBOCYTHEMIA1. Ann Intern Med. 1958;48:685–697. doi: 10.7326/0003-4819-48-3-685
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Published: Ann Intern Med. 1958;48(3):685-697.
Coagulopathies, Hematology/Oncology, Platelet Disorders.
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