ROBERT B. CHODOS, M.D., F.A.C.P.; JOSEPH F. ROSS, M.D., F.A.C.P.
Radioactive phosphorus is now generally accepted as an effective therapeutic agent for chronic leukemia and polycythemia vera. There is some disagreement, however, as to how it should be used in the treatment of patients with chronic leukemia. In most clinics, therapy of chronic leukemia with radiophosphorus has been initiated by the "fractional" or "saturation" methods of Low-Beer et al.16 Subsequent dosage has depended upon the clinical and hematologic response of the individual patient,2, 7, 10, 11 with additional radiophosphorus being administered only when there was evidence of progression of the disease. The resulting length of survival has been approximately that
CHODOS RB, ROSS JF. THE USE OF RADIOACTIVE PHOSPHORUS IN THE THERAPY OF LEUKEMIA, POLYCYTHEMIA VERA AND LYMPHOMAS: A REPORT OF 10 YEARS' EXPERIENCE1. Ann Intern Med. ;48:956–977. doi: 10.7326/0003-4819-48-5-956
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Published: Ann Intern Med. 1958;48(5):956-977.
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