JOHN H. LAWRENCE, M.D., D.SC., F.A.C.P.; WILLIAM G. DONALD JR., M.D.
Giant follicular lymphoblastoma was first identified as a distinct disease entity by Brill, Baehr and Rosenthal in 1925.1 Their original description was "benign giant follicle hyperplasia," but they soon recognized that it was, or could become, a malignant lymphoma.2, 3 Symmers4 in 1927 described a group of cases with the same findings which he termed "follicular lymphadenopathy." He considered this a benign condition, but later recognized that it is capable of transition into malignant disease of the lymphosarcoma group. Since these original descriptions, there has been a great deal of discussion and disagreement concerning the origin of the disease, and
LAWRENCE JH, DONALD WG. GIANT FOLLICULAR LYMPHOBLASTOMA: ITS TREATMENT WITH RADIOISOTOPES12. Ann Intern Med. 1958;49:1–16. doi: 10.7326/0003-4819-49-1-1
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Published: Ann Intern Med. 1958;49(1):1-16.
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