N. B. KURNICK, M.D., F.A.C.P.; ANDREW MONTANO, B.S.; JAMES C. GERDES, M.D.; BERNARD H. FEDER, M.D.
The work of Lorenz et al.1 on the protection of rodents against lethal x-radiation by the subsequent intravenous injection of bone marrow has been amply confirmed.2 Recent studies have demonstrated that the injected bone marrow cells repopulate the depleted bone marrow of the recipient.3, 4, 5, 6 Barnes and Loutit7 have demonstrated that the radiation-protective bone marrow elements can be preserved for at least 83 days by freezing in glycerol and storing in the cold. These authors have further reported the treatment of murine leukemia by lethal total-body irradiation, followed by homologous bone marrow injection.8 On the basis of
KURNICK NB, MONTANO A, GERDES JC, FEDER BH. PRELIMINARY OBSERVATIONS ON THE TREATMENT OF POSTIRRADIATION HEMATOPOIETIC DEPRESSION IN MAN BY THE INFUSION OF STORED AUTOGENOUS BONE MARROW1. Ann Intern Med. ;49:973–986. doi: 10.7326/0003-4819-49-5-973
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Published: Ann Intern Med. 1958;49(5):973-986.
Hematology/Oncology, Hospital Medicine.
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