JOHN B. JOHNSON, M.D., F.A.C.P.; AUDREY FAIRLEY, B.S.; CLARENCE CARTER, M.S.
The retrosternal distress associated with paroxysmal dyspnea may be quite severe, and in many instances it is described by the patient as pain.1 This discomfort is sometimes interpreted by the physician as the pain of angina pectoris, resulting in the administration of nitroglycerin.
In a recent publication we reported that frequently the retrosternal discomfort and breathlessness of paroxysmal dyspnea were promptly relieved by the sublingual administration of nitroglycerin. The clinical effectiveness of nitroglycerin over other emergency measures was so unmistakable in many of our patients that we now use the drug routinely, and the patients now insist on having the
JOHNSON JB, FAIRLEY A, CARTER C. EFFECTS OF SUBLINGUAL NITROGLYCERIN ON PULMONARY ARTERIAL PRESSURE IN PATIENTS WITH LEFT VENTRICULAR FAILURE*†. Ann Intern Med. 1959;50:34–42. doi: https://doi.org/10.7326/0003-4819-50-1-34
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Published: Ann Intern Med. 1959;50(1):34-42.
Cardiology, Heart Failure, Pulmonary/Critical Care.
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