RUSSELL E. RANDALL JR.; ELSIE C. ROSSMEISL; KENNETH H. BLEIFER
The discovery of a neuromuscular disorder in animals specifically related to a deficiency of magnesium1-9 has led to investigation of this ion in various clinical disorders in man.10-31 Studies have been seriously handicapped by several factors. The quantitative determination of magnesium has proved troublesome, particularly with the older precipitation methods.32-34 The current methods employing colorimetric technics,35-37 and the newer methods employing flame photometry,38 spectrography39-41 and versene chelation,42-44 are rapidly overcoming this barrier. The natural distribution of the magnesium ion has been a particularly troublesome problem. Its location chiefly within cells and bone makes difficult the interpretation of many studies concerned
RANDALL RE, ROSSMEISL EC, BLEIFER KH. MAGNESIUM DEPLETION IN MAN*. Ann Intern Med. 1959;50:257–287. doi: https://doi.org/10.7326/0003-4819-50-2-257
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Published: Ann Intern Med. 1959;50(2):257-287.
Hospital Medicine, Nephrology.
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