JOHN T. GALAMBOS, M.D.; LAMAR B. PEACOCK, M.D.
Recent reports advocate the use of chelating agents in the treatment of porphyria hepatica. The following case is described to point out that the administration of a chelating agent may be followed by prompt and clear-cut worsening of the clinical state of the patient with acute intermittent porphyria (AIP).
A 50 year old white man had been working in a metal casket manufacturing company and had been exposed intimately to zinc metal and lead dust for approximately 17 years. He had felt well until December 1, 1956, when he began to have cramping abdominal pains and marked constipation.
GALAMBOS JT, PEACOCK LB. THE USE OF CHELATING AGENTS IN THE TREATMENT OF ACUTE PORPHYRIA*. Ann Intern Med. 1959;50:1056–1061. doi: https://doi.org/10.7326/0003-4819-50-4-1056
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Published: Ann Intern Med. 1959;50(4):1056-1061.
Gastroenterology/Hepatology, Liver Disease.
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