PAUL CALABRESI, M.D.; OVID O. MEYER, M.D., F.A.C.P.
Originally described by Vaquez1 in 1892, polycythemia vera was established as a definite clinical entity by the subsequent reports of Saundby and Russell2 and Osler3, 4 at the turn of the century. The early historical and investigative accounts of this condition have been thoroughly reviewed in the literature.5, 6, 7
By 1940 two distinct contributions had been made which laid the foundation for our present-day concepts of the nature and therapy of the disease: (1) the description of the various clinical stages of the disease by Rosenthal and Bassen,8 and (2) the introduction of radioactive phosphorus by Lawrence.9 Notwithstanding these
CALABRESI P, MEYER OO. POLYCYTHEMIA VERA. I. CLINICAL AND LABORATORY MANIFESTATIONS1. Ann Intern Med. 1959;50:1182–1202. doi: 10.7326/0003-4819-50-5-1182
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Published: Ann Intern Med. 1959;50(5):1182-1202.
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