ELLEN M. LESSMANN; JOSEPH E. SOKAL
The association of pregnancy and leukemia is rare.1, 2 There has been much interest in this subject, and several comprehensive reviews have been published.3, 4, 5 The dangers of x-ray irradiation therapy in pregnant women have been well documented.6, 7 However, very little information is available on the effects of antileukemic chemotherapy on the course of pregnancy and on the fetus. This report deals with a patient who conceived, had an uneventful pregnancy, and was delivered of a normal infant while under continuous therapy with the antimitotic agent, Colcemide.†
Colcemide (also known as Demecolcin), an alkaloid closely related to colchicine,
LESSMANN EM, SOKAL JE. CONCEPTION AND PREGNANCY IN A PATIENT WITH CHRONIC MYELOCYTIC LEUKEMIA UNDER CONTINUOUS COLCEMIDE THERAPY1. Ann Intern Med. 1959;50:1512–1518. doi: 10.7326/0003-4819-50-6-1512
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Published: Ann Intern Med. 1959;50(6):1512-1518.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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