BARNEY MALBIN, M.D.
About eight years ago Engel and von Euler1 suggested that the quantitative determination of the catechol amines in the urine might be a practical procedure for the diagnosis of pheochromocytoma. Since then a number of investigators2, 3, 4, 5 have confirmed their experience and expanded their conclusions, so that today the presence of large excesses of epinephrine and/or norepinephrine in the urine is generally regarded as pathognomonic of this disease.
Therefore, when a case presents the findings of so-called diagnostic levels of the catechol amines in the urine, and no tumor can be found, it merits interest and consideration. Such
MALBIN B. EXCESS URINARY CATECHOL AMINES WITHOUT PHEOCHROMOCYTOMA*. Ann Intern Med. 1959;51:613–617. doi: https://doi.org/10.7326/0003-4819-51-3-613
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Published: Ann Intern Med. 1959;51(3):613-617.
Adrenal Disorders, Endocrine and Metabolism, Endocrine Cancer, Hematology/Oncology.
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