BARNEY MALBIN, M.D.
About eight years ago Engel and von Euler1 suggested that the quantitative determination of the catechol amines in the urine might be a practical procedure for the diagnosis of pheochromocytoma. Since then a number of investigators2, 3, 4, 5 have confirmed their experience and expanded their conclusions, so that today the presence of large excesses of epinephrine and/or norepinephrine in the urine is generally regarded as pathognomonic of this disease.
Therefore, when a case presents the findings of so-called diagnostic levels of the catechol amines in the urine, and no tumor can be found, it merits interest and consideration. Such
MALBIN B. EXCESS URINARY CATECHOL AMINES WITHOUT PHEOCHROMOCYTOMA1. Ann Intern Med. 1959;51:613–617. doi: 10.7326/0003-4819-51-3-613
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Published: Ann Intern Med. 1959;51(3):613-617.
Adrenal Disorders, Endocrine and Metabolism, Endocrine Cancer, Hematology/Oncology.
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