G. LENNARD GOLD, M.D.; BRUCE I. SHNIDER, M.D.
It is usual for patients with malignant neoplasms to present with symptoms and signs produced by the anatomic location of their tumor or its metastases. Occasionally, as is the case with functioning endocrine tumors, the products of the neoplastic growths are responsible for many of the manifestations.
More recently, several abnormalities of body metabolism have been recognized in some people afflicted with neoplastic growths. Cerebellar degeneration and various neurologic syndromes have been reported in association with malignant tumors, despite the fact that no metastatic deposits could be found. Cushing's syndrome, mineralocorticoid abnormalities, hypoglycemia, hypercalcemia and polycythemia have been recorded in
GOLD GL, SHNIDER BI. SOME UNUSUAL SYNDROMES ASSOCIATED WITH NEOPLASTIC DISEASE1. Ann Intern Med. 1959;51:890–896. doi: 10.7326/0003-4819-51-5-890
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Published: Ann Intern Med. 1959;51(5):890-896.
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