M. R. SHETLAR, Ph.D.; R. W. PAYNE, M.D.; GEORGE STIDWORTHY, M.S.; DAVID MOCK, M.D.
Albumin is the most abundant serum protein component in the normal human being. This major serum protein component is of obvious importance in providing a major portion of the osmotic pressure of serum; in addition, it performs important transport functions. Bennhold1 has described two related individuals whose sera were lacking in albumin. These patients were a woman in apparently good health except for occasional slight edema, and a brother with the same defect found during a familial study.
The present report deals with studies of a patient with severe, classic rheumatoid arthritis who, in addition, exhibited a virtual analbuminemia.
SHETLAR MR, PAYNE RW, STIDWORTHY G, et al. ABSENCE OF SERUM ALBUMIN ASSOCIATED WITH RHEUMATOID ARTHRITIS12. Ann Intern Med. 1959;51:1379–1384. doi: 10.7326/0003-4819-51-6-1379
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Published: Ann Intern Med. 1959;51(6):1379-1384.
Rheumatoid Arthritis, Rheumatology.
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