CHARLES G. CRADDOCK JR., M.D., F.A.C.P.; SEYMOUR PERRY, M.D., F.A.C.P.; JOHN S. LAWRENCE, M.D., F.A.C.P.
Many features of the physiology of leukocytes are controversial. The origin of certain cells—for example, the monocyte and the plasma cell—is disputed. The functions of many of the cell species (e.g., the variously sized lymphocytes, the eosinophil, the basophil) are still conjectural, despite recent advances in cytochemistry. The lymphocyte has been implicated in such fundamental processes as immune globulin synthesis, antibody transport,1 and the transmission of genetic material or information to proliferating tissues.2 They have also been described as "pluripotential" cells, capable of differentiation into other hemic cells.3
In contrast to these less well defined and esoteric functions of other
CRADDOCK CG, PERRY S, LAWRENCE JS. THE DYNAMICS OF LEUKOPENIA AND LEUKOCYTOSIS*†. Ann Intern Med. 1960;52:281–294. doi: https://doi.org/10.7326/0003-4819-52-2-281
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Published: Ann Intern Med. 1960;52(2):281-294.
Gastroenterology/Hepatology, Hematology/Oncology, Hospital Medicine.
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