WILLIAM H. SAUNDERS, M.D.
Recurrent familial epistaxis was first recognized by Babbington1 in 1865. He reported "hereditary epistaxis" in five generations of a family. Legg in 18762 confused the disorder with hemophilia, as did Chiari in 18873 and Chauffard in 1896.4 Rendu5 distinguished it from hemophilia in 1896. Meanwhile Osler,6 at The Johns Hopkins Hospital, had been observing three patients with the disorder, and in 1901 published his classic description, "On a Family Form of Recurring Epistaxis with Multiple Telangiectases of the Skin and Mucous Membranes."
After Osler's account, Kelly in 19067 presented excellent color drawings of patients with multiple telangiectases. Weber9 described a
SAUNDERS WH. PERMANENT CONTROL OF NOSEBLEEDS IN PATIENTS WITH HEREDITARY HEMORRHAGIC TELANGIECTASIA1. Ann Intern Med. 1960;53:147–152. doi: 10.7326/0003-4819-53-1-147
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Published: Ann Intern Med. 1960;53(1):147-152.
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