ALBERT G. LEWIS JR., M.D.; EUNICE M. LASCHÉ, M.D.; ALLAN L. ARMSTRONG, M.D.; FRANK P. DUNBAR
Before the development of cultural methods, the diagnosis of tuberculosis was based upon the finding of acid-fast bacilli on microscopic examination, positive tuberculin skin test, and characteristic x-ray and histologic changes. It is now recognized that all of these findings may be present in other chronic lung infections. The clinical entity of such diseases produced by acid-fast bacilli other than the tubercle bacillus has assumed increasing importance recently, although it has been reported sporadically for many years.1-14 The internist is confronted more frequently now with chronic pulmonary disease due to atypical mycobacteria.
Various bacteriologic methods have resulted in the identification
LEWIS AG, LASCHÉ EM, ARMSTRONG AL, DUNBAR FP. A CLINICAL STUDY OF THE CHRONIC LUNG DISEASE DUE TO NONPHOTOCHROMOGENIC ACID-FAST BACILLI12. Ann Intern Med. ;53:273–285. doi: 10.7326/0003-4819-53-2-273
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Published: Ann Intern Med. 1960;53(2):273-285.
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