MORTIMER LORBER, M.D.
Gaucher's disease is a metabolic disorder characterized by the presence in various organs of large cells containing the cerebroside, kerasin.1, 2 These cells are found in greatest number in the bone marrow, spleen, liver and lymph nodes,3 structures which also contain the bulk of the reticuloendothelial cells of the body. The latter are believed to be the progenitors of Gaucher cells,4, 6 in addition to their other functions, which include a role in the metabolism and storage of iron.7-12 Earlier papers have disagreed as to the distribution of tissue iron in this disorder; it has therefore been deemed worth while
LORBER M. THE OCCURRENCE OF INTRACELLULAR IRON IN GAUCHER'S DISEASE12. Ann Intern Med. ;53:293–305. doi: 10.7326/0003-4819-53-2-293
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Published: Ann Intern Med. 1960;53(2):293-305.
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