WILLIAM MCFARLAND; HOWARD A. PEARSON
In 1925 and 1927 Cooley and Lee1, 2 described an anemia peculiar to individuals of Greek or Italian origin. Subsequently, the disease has been so thoroughly studied and documented that thalassemia is one of the first diagnostic considerations in an individual of "Mediterranean background" who presents with hypochromic anemia. However, the disease is rarely entertained as a diagnostic possibility in the absence of such an ethnic background, in spite of the fact that there have been numerous reports of the disease in other racial groups in almost all parts of the world.
One reason for hesitancy to diagnose thalassemia in
MCFARLAND W, PEARSON HA. THALASSEMIA IN "NON-MEDITERRANEAN" FAMILIES1. Ann Intern Med. 1960;53:510–522. doi: 10.7326/0003-4819-53-3-510
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Published: Ann Intern Med. 1960;53(3):510-522.
Hematology/Oncology, Red Cell Disorders.
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