KURT LANGE, M.D., F.A.C.P.; EDWARD WASSERMAN, M.D.; LAWRENCE B. SLOBODY, M.D.
Since the original publication by Veil and Buchholz1 in 1932, in which they reported a lowering of serum complement in a few cases of acute glomerulonephritis, a number of investigators have studied this phenomenon, mostly in small numbers of cases and with short-term observations only.2, 3, 4
For the last 10 years5, 6 we have examined serum complement levels in 3,051 patients with varied kidney diseases, in addition to examinations in a great number of normal persons, and in patients with other disease conditions. Since we felt that the determination of serum complement levels (C') is an important and often
LANGE K, WASSERMAN E, SLOBODY LB. THE SIGNIFICANCE OF SERUM COMPLEMENT LEVELS FOR THE DIAGNOSIS AND PROGNOSIS OF ACUTE AND SUBACUTE GLOMERULONEPHRITIS AND LUPUS ERYTHEMATOSUS DISSEMINATUS12. Ann Intern Med. 1960;53:636–646. doi: 10.7326/0003-4819-53-4-636
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Published: Ann Intern Med. 1960;53(4):636-646.
Autoimmune Kidney Disease, Lupus Erythematosus, Nephrology, Rheumatology.
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