JOHN M. FIORE, M.D.; WILLIAM T. SMYTH, M.D.
The syndrome of acute spontaneous absorption of bone is a rather rare and poorly understood condition. It is often referred to under such descriptive titles as "disappearing bone," "acute spontaneous absorption of bone," "phantom bone" and "idiopathic osteolysis of bone." In the cases reported to date, several common factors seem to occur repeatedly: The patient is usually a young adult in good general health; minor trauma, usually to the affected area, calls attention to the lesion; pain is not a striking symptom; there is no sex predilection. The course of the disease is variable. Cases have been reported where the
FIORE JM, SMYTH WT. MASSIVE OSTEOLYSIS OF BONE: REPORT OF A FATAL CASE WITH TEMPORARY RECONSTITUTION OF THE AFFECTED BONE FOLLOWING IRRADIATION*. Ann Intern Med. 1960;53:807–816. doi: https://doi.org/10.7326/0003-4819-53-4-807
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Published: Ann Intern Med. 1960;53(4):807-816.
Hematology/Oncology, Hospital Medicine.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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