CHARLES A. DOAN, M.D., F.A.C.P.; BERTHA A. BOURONCLE, M.D.; BRUCE K. WISEMAN, M.D., F.A.C.P.
For the last 28 years we have been concerned with the study of thrombocytopenic purpura. Our spiraling interest has paralleled the progressive increase in the total number of patients with this syndrome seen in our Hematology Clinics in each five-year period (figure 1).
Until 1950 the only major effective therapeutic procedure available was splenectomy. Since then, corticosteroids have been selectively employed and recommended.
The purpose of this study is to present an evaluation of the clinical and hematologic findings in thrombocytopenic purpura; to establish a comparison of the results obtained with splenectomy versus corticosteroid therapy; to report the postsplenectomy life
DOAN CA, BOURONCLE BA, WISEMAN BK. IDIOPATHIC AND SECONDARY THROMBOCYTOPENIC PURPURA: CLINICAL STUDY AND EVALUATION OF 381 CASES OVER A PERIOD OF 28 YEARS*. Ann Intern Med. 1960;53:861–876. doi: https://doi.org/10.7326/0003-4819-53-5-861
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Published: Ann Intern Med. 1960;53(5):861-876.
Coagulopathies, Hematology/Oncology, Platelet Disorders.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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