JOSEPH PICCHI, M.D.; ALAN R. NELSON, M.D.; EDWARD E. WALLER, M.D.; MOHAMAD RAZAVI, M.D.; EDWIN E. CLIZER, M.D.
Q fever is an acute febrile disease with systemic manifestations, caused by the rickettsia Coxiella burnetii, and usually transmitted by inhalation, without an intermediate vector. It has now been reported throughout the world, and is endemic in many parts of the United States, especially California. Emphasis is usually placed on the pulmonary aspects of the disease; however, we are reporting three cases of Q fever that came under our care during a recent epidemic in Alameda County, each presenting as hepatitis with inconspicuous or absent pulmonary findings. Liver biopsy in all three cases demonstrated a diffuse granulomatous process with multinucleated
PICCHI J, NELSON AR, WALLER EE, et al. Q FEVER ASSOCIATED WITH GRANULOMATOUS HEPATITIS*. Ann Intern Med. 1960;53:1065–1074. doi: https://doi.org/10.7326/0003-4819-53-5-1065
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Published: Ann Intern Med. 1960;53(5):1065-1074.
Gastroenterology/Hepatology, Infectious Disease, Liver Disease.
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