STEPHEN E. EPSTEIN; E. LOVELL BECKER, M.D.
Kimmelstiel and Wilson1 in 1936 first described the nodular lesion found in the glomeruli of patients with diabetes. Their original study was based on autopsy findings and included an evaluation of the associated clinical findings. Since that time, many studies of the clinical syndrome associated with this lesion have been reported. However, percutaneous renal biopsy has made it possible to evaluate the specific relationship between the clinical signs and symptoms and the pathologic lesion studied. Since a variety of diseases can produce the same clinical manifestations, careful clinical and laboratory investigation are required to establish the correct diagnosis.
EPSTEIN SE, BECKER EL. ACUTE GLOMERULONEPHRITIS IN AN ADULT WITH LONGSTANDING DIABETES MELLITUS12. Ann Intern Med. ;54:97–103. doi: 10.7326/0003-4819-54-1-97
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Published: Ann Intern Med. 1961;54(1):97-103.
Cardiology, Coronary Risk Factors, Diabetes, Diabetic Nephropathy, Endocrine and Metabolism.
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