J. CHANDLER SMITH, M.D.
Cases of diffuse metastatic intrasinusoidal cancer of the liver are unique in both clinical and morphologic aspects. The clinical features include a silent and often substantial interval between the primary illness and the detection of metastasis, as well as an unusually rapid terminal course. The clinical diagnosis is often obscure, and the laboratory procedure most likely to establish the correct diagnosis has frequently not been used. The morphologic findings include an unusual distribution of metastases and an unusual location of the tumor cells within the tissues involved. In addition, the morphologic and clinical features indicate an uncommon tumor-host relationship, and
SMITH JC. DIFFUSE INTRASINUSOIDAL METASTATIC CANCER OF THE LIVER1. Ann Intern Med. ;54:104–113. doi: 10.7326/0003-4819-54-1-104
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Published: Ann Intern Med. 1961;54(1):104-113.
Gastroenterology/Hepatology, Liver Disease.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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