ROBERT B. ERICHSON, M.D.; M. J. MCNAMARA, M.D.
Vaccinia gangrenosa is a rare complication of smallpox vaccination characterized by progressive spread and necrosis of the primary inoculation site, metastatic vaccinial lesions, sometimes occurring in multiple outcroppings, and a uniformly fatal outcome when not specifically treated. Of the several important complications of smallpox vaccination, it is the least common and has the poorest prognosis. The following case is the twelfth to be reported fully in the literature in English, the third involving an adult, and the third in which the disease itself was not fatal.
A 58-year-old white man was admitted to The New York Hospital on
ERICHSON RB, MCNAMARA MJ. Vaccinia Gangrenosa: Report of a Case and Review of the Literature. Ann Intern Med. 1961;55:491–498. doi: https://doi.org/10.7326/0003-4819-55-3-491
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Published: Ann Intern Med. 1961;55(3):491-498.
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