J. H. BOSS, M.D.; M. LEFFKOWITZ, M.D.; M. FREUD, M.D.
The salient clinical and pathological features of syphilitic cardiovascular disease are well known, yet a unique case may still pose perplexing and intriguing problems. In the case reported, myxomatous degeneration of the cardiovascular connective tissue is the notable pathological finding. Myxomatous material, a normal body constituent, accumulates with increasing age and in certain pathological conditions in the heart and blood vessels (1, 2). The purpose of this report is to stress the anatomical and functional significance of myxomatous degeneration in syphilitic cardiovascular disease.
A 36-year-old sanitation worker was referred to this hospital because of "arthralgia." He had no
BOSS JH, LEFFKOWITZ M, FREUD M. Unusual Manifestations of Syphilitic Cardiovascular Disease. Ann Intern Med. 1961;55:824–831. doi: 10.7326/0003-4819-55-5-824
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Published: Ann Intern Med. 1961;55(5):824-831.
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