JOHN S. CHAPMAN, M.D., F.A.C.P.
In the official pronouncement of the Committee on Sarcoidosis of the National Research Council, sarcoidosis is a "disease of unknown etiology." This view is not universally accepted. Since Pinner's description of sarcoidosis as an anergic form of tuberculosis (1), a view most notably seconded by Scadding (2), discussion has involved not only the tuberculous etiology, but also the possibility that ultimately the condition known as sarcoidosis may result from identical reactions to many different agents. The multitudinous possibilities have been ably expounded by Refvem (3).
In general, American authors have agreed with the opinion of Lofgren (4) that sarcoidosis is
CHAPMAN JS. Mycobacterial and Mycotic Antibodies in Sera of Patients with Sarcoidosis: Results of Studies Using Agar Double-diffusion Technique. Ann Intern Med. ;55:918–924. doi: 10.7326/0003-4819-55-6-918
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Published: Ann Intern Med. 1961;55(6):918-924.
Infectious Disease, Mycobacterial Infections.
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