ROBERT R. BURCH, M.D.; MAURICE A. PEARL, M.D.; WILLIAM H. STERNBERG, M.D.
The nephrotic syndrome is a disorder of diverse causes which occurs as a primary or secondary form of renal disease and exhibits variable pathologic features (1-8). Its etiologic and pathologic variations pose many problems of diagnosis and therapy. However, a pathologic diagnosis can now be made by a percutaneous renal biopsy. Such biopsies have revealed the broad spectrum of histopathologic changes found in the group of diseases responsible for the nephrotic syndrome (5-14). The multiple glomerular changes revealed by renal biopsies may help to explain the marked variation in the clinical course, as well as unpredictable and variable responses to
BURCH RR, PEARL MA, STERNBERG WH. A Clinicopathological Study of the Nephrotic Syndrome. Ann Intern Med. ;56:54–67. doi: 10.7326/0003-4819-56-1-54
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Published: Ann Intern Med. 1962;56(1):54-67.
Nephrology, Nephrotic Syndrome.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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