P. D. Doolan; H. A. Harper, Ph.D.
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Previous studies in this laboratory have shown that in normal human subjects virtually the entire quantity of the amino acids filtered by the glomerulus of the kidney is reabsorbed by the tubules. With infusions of a mixture of free individual amino acids and a consequent increase in the filtered load, both the amounts reabsorbed and excreted are increased. Despite considerable selectivity among the amino acids, the capacity for reabsorption is such that to date no maximal rate of reabsorption (Tm) for any amino acid has been demonstrated in the human. The amounts filtered are therefore prime determinants of the amounts
Doolan PD, Harper HA. Aminoaciduria: A Discussion of its Mechanism.. Ann Intern Med. ;56:697. doi: 10.7326/0003-4819-56-4-697_1
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Published: Ann Intern Med. 1962;56(4):697.
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